Targeting the DNA damage response and repair in cancer through nucleotide metabolism
Author:
Affiliation:
1. Science for Life Laboratory Department of Oncology‐Pathology Karolinska Institutet Stockholm Sweden
2. Department of Oncology and Metabolism, Weston Park Cancer Centre University of Sheffield UK
Funder
Barncancerfonden
Cancerfonden
Dr Åke Olssons Stiftelse för Haematologisk Forskning
Karolinska Institutet
Novo Nordisk Fonden
Sjöbergstiftelsen
Vetenskapsrådet
Publisher
Wiley
Subject
Cancer Research,Genetics,Molecular Medicine,General Medicine,Oncology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/1878-0261.13227
Reference173 articles.
1. Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints
2. Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication
3. An Oncogene-Induced DNA Damage Model for Cancer Development
4. Mechanisms underlying mutational signatures in human cancers
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