Rapid generation of potent antibodies by autonomous hypermutation in yeast-Reference-Cited by-同舟云学术

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Rapid generation of potent antibodies by autonomous hypermutation in yeast

Published:2021-06-24 Issue:10 Volume:17 Page:1057-1064
ISSN:1552-4450
Container-title:Nature Chemical Biology
language:en
Short-container-title:Nat Chem Biol

Author:

Wellner Alon,McMahon Conor,Gilman Morgan S. A.,Clements Jonathan R.,Clark Sarah^ORCID,Nguyen Kianna M.,Ho Ming H.,Hu Vincent J.^ORCID,Shin Jung-Eun,Feldman Jared,Hauser Blake M.,Caradonna Timothy M.^ORCID,Wingler Laura M.^ORCID,Schmidt Aaron G.^ORCID,Marks Debora S.,Abraham Jonathan,Kruse Andrew C.^ORCID,Liu Chang C.^ORCID

Funder

U.S. Department of Health & Human Services | National Institutes of Health

Massachusetts Consortium on Pathogenesis Readiness

Vallee Foundation

Gordon and Betty Moore Foundation

UC | University of California, Irvine

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Molecular Biology

Link

https://www.nature.com/articles/s41589-021-00832-4.pdf

Reference55 articles.

1. Lu, R. M. et al. Development of therapeutic antibodies for the treatment of diseases. J. Biomed. Sci. 27, 1 (2020).

2. Gravbrot et al. Therapeutic monoclonal antibodies targeting immune checkpoints for the treatment of solid tumors. Antibodies 8, 51 (2019).

3. Czajka, T. F., Vance, D. J. & Mantis, N. J. Slaying SARS-CoV-2 one (single-domain) antibody at a time. Trends Microbiol. 29, 195–203 (2021).

4. Byrne, B., Stack, E., Gilmartin, N. & O’Kennedy, R. Antibody-based sensors: principles, problems and potential for detection of pathogens and associated toxins. Sensors 9, 4407–4445 (2009).

5. Yao, H. et al. Patient-derived SARS-CoV-2 mutations impact viral replication dynamics and infectivity in vitro and with clinical implications in vivo. Cell Discov. 6, 76 (2020).

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