MutaT7<sup>GDE</sup>: A Single Chimera for the Targeted, Balanced, Efficient, and Processive Installation of All Possible Transition Mutations <i>In Vivo</i>-Reference-Cited by-同舟云学术

MutaT7^GDE: A Single Chimera for the Targeted, Balanced, Efficient, and Processive Installation of All Possible Transition Mutations In Vivo

Published:2024-08-27 Issue: Volume: Page:
ISSN:2161-5063
Container-title:ACS Synthetic Biology
language:en
Short-container-title:ACS Synth. Biol.

Author:

Mengiste Amanuella A.¹,McDonald Julie L.²,Nguyen Tran Minh Thuan¹,Plank Anna V.²³,Wilson Robert H.¹,Butty Vincent L.⁴,Shoulders Matthew D.¹⁵⁶^ORCID

Affiliation:

1. Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States

2. Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States

3. Department of Brain and Cognitive Sciences, Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States

4. BioMicroCenter, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States

5. Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02139, United States

6. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States

Funder

National Institute of Environmental Health Sciences

National Cancer Institute

Massachusetts Institute of Technology

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acssynbio.4c00316

Reference47 articles.

1. Directed Evolution: Methodologies and Applications

2. Methods for the directed evolution of proteins

3. In vivo hypermutation and continuous evolution

4. The Mechanisms of UV Mutagenesis

5. A review of the genetic effects of ethyl methanesulfonate