Estrogen enhances the functions of CD4+CD25+Foxp3+ regulatory T cells that suppress osteoclast differentiation and bone resorption in vitro
Author:
Publisher
Springer Science and Business Media LLC
Subject
Infectious Diseases,Immunology,Immunology and Allergy
Link
http://www.nature.com/articles/cmi201054.pdf
Reference32 articles.
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3. D'Amelio P, Grimaldi A, Di Bella S, Tamone C, Brianza SZ, Ravazzoli MG et al. Estrogen deficiency increases osteoclastogenesis up-regulating T cells activity: a key mechanism in osteoporosis. Bone 2008; 43: 92–100.
4. Tanaka S, Takahashi N, Udagawa N, Tamura T, Akatsu T, Stanley ER et al. Macrophage colony-stimulating factor is indispensable for both proliferation and differentiation of osteoclast progenitors. J Clin Invest 1993; 91: 257–263.
5. Theill LE, Boyle WJ, Penninger JM . RANKL and RANK: T cells, bone loss, and mammalian evolution. Annu Rev Immunol 2002; 20: 795–823.
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