Efficient in vitro and in vivo RNA editing via recruitment of endogenous ADARs using circular guide RNAs-Reference-Cited by-同舟云学术

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Efficient in vitro and in vivo RNA editing via recruitment of endogenous ADARs using circular guide RNAs

Published:2022-02-10 Issue:6 Volume:40 Page:938-945
ISSN:1087-0156
Container-title:Nature Biotechnology
language:en
Short-container-title:Nat Biotechnol

Author:

Katrekar Dhruva,Yen James,Xiang Yichen,Saha Anushka,Meluzzi Dario,Savva Yiannis,Mali Prashant^ORCID

Funder

U.S. Department of Health & Human Services | NIH | National Human Genome Research Institute

U.S. Department of Health & Human Services | NIH | National Cancer Institute

U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences

Publisher

Springer Science and Business Media LLC

Subject

Biomedical Engineering,Molecular Medicine,Applied Microbiology and Biotechnology,Bioengineering,Biotechnology

Link

https://www.nature.com/articles/s41587-021-01171-4.pdf

Reference47 articles.

1. Melcher, T. et al. A mammalian RNA editing enzyme. Nature 379, 460–464 (1996).

2. Bass, B. L. & Weintraub, H. An unwinding activity that covalently modifies its double-stranded RNA substrate. Cell 55, 1089–1098 (1988).

3. Bass, B. L. & Weintraub, H. A developmentally regulated activity that unwinds RNA duplexes. Cell 48, 607–613 (1987).

4. Mannion, N. M. et al. The RNA-editing enzyme ADAR1 controls innate immune responses to RNA. Cell Rep. 9, 1482–1494 (2014).

5. Tomaselli, S. et al. Modulation of microRNA editing, expression and processing by ADAR2 deaminase in glioblastoma. Genome Biol. 16, 5 (2015).

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