Robust genome and cell engineering via in vitro and in situ circularized RNAs-Reference-Cited by-同舟云学术

Robust genome and cell engineering via in vitro and in situ circularized RNAs

Published:2024-08-26 Issue: Volume: Page:
ISSN:2157-846X
Container-title:Nature Biomedical Engineering
language:en
Short-container-title:Nat. Biomed. Eng

Author:

Tong Michael,Palmer Nathan,Dailamy Amir,Kumar Aditya,Khaliq Hammza,Han Sangwoo,Finburgh Emma,Wing Madeleine,Hong Camilla,Xiang Yichen,Miyasaki Katelyn,Portell Andrew,Rainaldi Joseph,Suhardjo Amanda,Nourreddine Sami,Chew Wei Leong,Kwon Ester J.,Mali Prashant^ORCID

Funder

U.S. Department of Health & Human Services | National Institutes of Health

U.S. Department of Defense

U.S. Department of Health & Human Services | NIH | Office of Extramural Research, National Institutes of Health

American Heart Association

Publisher

Springer Science and Business Media LLC

Link

https://www.nature.com/articles/s41551-024-01245-z.pdf

Reference110 articles.

1. Karikó, K., Muramatsu, H., Ludwig, J. & Weissman, D. Generating the optimal mRNA for therapy: HPLC purification eliminates immune activation and improves translation of nucleoside-modified, protein-encoding mRNA. Nucleic Acids Res. 39, e142 (2011).

2. Presnyak, V. et al. Codon optimality is a major determinant of mRNA stability. Cell 160, 1111–1124 (2015).

3. Kuhn, A. N. et al. Phosphorothioate cap analogs increase stability and translational efficiency of RNA vaccines in immature dendritic cells and induce superior immune responses in vivo. Gene Ther. 17, 961–971 (2010).

4. Holtkamp, S. et al. Modification of antigen-encoding RNA increases stability, translational efficacy, and T-cell stimulatory capacity of dendritic cells. Blood 108, 4009–4017 (2006).

5. Orlandini von Niessen, A. G. et al. Improving mRNA-based therapeutic gene delivery by expression-augmenting 3′ UTRs identified by cellular library screening. Mol. Ther. 27, 824–836 (2019).