Targeting herpes simplex virus with CRISPR–Cas9 cures herpetic stromal keratitis in mice
Author:
Publisher
Springer Science and Business Media LLC
Subject
Biomedical Engineering,Molecular Medicine,Applied Microbiology and Biotechnology,Bioengineering,Biotechnology
Link
http://www.nature.com/articles/s41587-020-00781-8.pdf
Reference48 articles.
1. Liesegang, T. J. Herpes simplex virus epidemiology and ocular importance. Cornea 20, 1–13 (2001).
2. Paludan, S. R., Bowie, A. G., Horan, K. A. & Fitzgerald, K. A. Recognition of herpesviruses by the innate immune system. Nat. Rev. Immunol. 11, 143–154 (2011).
3. Bradshaw, M. J. & Venkatesan, A. Herpes simplex virus-1 encephalitis in adults: pathophysiology, diagnosis, and management. Neurotherapeutics 13, 493–508 (2016).
4. Farooq, A. V. & Shukla, D. Herpes simplex epithelial and stromal keratitis: an epidemiologic update. Surv. Ophthalmol. 57, 448–462 (2012).
5. Crumpacker, C. S. & Schaffer, P. A. New anti-HSV therapeutics target the helicase–primase complex. Nat. Med. 8, 327–328 (2002).
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