Gemcitabine diphosphate choline is a major metabolite linked to the Kennedy pathway in pancreatic cancer models in vivo-Reference-Cited by-同舟云学术

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Gemcitabine diphosphate choline is a major metabolite linked to the Kennedy pathway in pancreatic cancer models in vivo

Published:2014-05-29 Issue:2 Volume:111 Page:318-325
ISSN:0007-0920
Container-title:British Journal of Cancer
language:en
Short-container-title:Br J Cancer

Author:

Bapiro T E,Frese K K,Courtin A,Bramhall J L,Madhu B,Cook N,Neesse A,Griffiths J R,Tuveson D A,Jodrell D I,Richards F M

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology

Link

http://www.nature.com/articles/bjc2014288.pdf

Reference36 articles.

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2. Arshad A, Chung W, Isherwood J, Steward W, Metcalfe M, Dennison A (2013a) Restoration of mannose-binding lectin complement activity is associated with improved outcome in patients with advanced pancreatic cancer treated with gemcitabine and intravenous omega-3 fish oil. JPEN J Parenter Enteral Nutr 38 (2): 214–219.

3. Arshad A, Chung WY, Steward W, Metcalfe MS, Dennison AR (2013b) Reduction in circulating pro-angiogenic and pro-inflammatory factors is related to improved outcomes in patients with advanced pancreatic cancer treated with gemcitabine and intravenous omega-3 fish oil. HPB (Oxford) 15 (6): 428–432.

4. Bapiro TE, Richards FM, Goldgraben MA, Olive KP, Madhu B, Frese KK, Cook N, Jacobetz MA, Smith DM, Tuveson DA, Griffiths JR, Jodrell DI (2011) A novel method for quantification of gemcitabine and its metabolites 2′,2′-difluorodeoxyuridine and gemcitabine triphosphate in tumour tissue by LC-MS/MS: comparison with (19)F NMR spectroscopy. Cancer Chemother Pharmacol 68 (5): 1243–1253.

5. Ben-Kasus T, Ben-Zvi Z, Marquez VE, Kelley JA, Agbaria R (2005) Metabolic activation of zebularine, a novel DNA methylation inhibitor, in human bladder carcinoma cells. Biochem Pharmacol 70 (1): 121–133.

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