Genetic architecture of the inflammatory bowel diseases across East Asian and European ancestries

Author:

Liu ZhanjuORCID,Liu Ruize,Gao Han,Jung SeulgiORCID,Gao Xiang,Sun Ruicong,Liu Xiaoming,Kim Yongjae,Lee Ho-Su,Kawai YosukeORCID,Nagasaki MasaoORCID,Umeno JunjiORCID,Tokunaga KatsushiORCID,Kinouchi Yoshitaka,Masamune AtsushiORCID,Shi Wenzhao,Shen Chengguo,Guo Zhenglin,Yuan KaiORCID,Abreu Maria,Achkar Jean-Paul,Andersen Vibeke,Bernstein Charles,Brant Steven R.,Bujanda Luis,Ng Siew Chien,Denson Lee A.,Duerr Richard H.,Ferguson Lynnette R.,Franchimont Denis,Franke Andre,Gearry Richard,Hakonarson Hakon,Halfvarson Jonas,Heller Caren,Julià Antonio,Kelsen Judith,Khalili Hamed,Kugathasan Subramaniam,Kupcinskas Juozas,Latiano Anna,Louis Edouard,Malekzadeh Reza,McCauley Jacob L.,Moran Christopher,Okou David,Orchard Tim,Palotie Aarno,Parkes Miles,Pekow Joel,Potočnik Uroš,Radford-Smith Graham,Rioux John D.,Rogler Gerhard,Sands Bruce,Silverberg Mark,Sokol Harry,Vermeire Séverine,Weersma Rinse K.,Xavier Ramnik J.,Hu Naizhong,Cao Qian,Wang Yufang,Miao Yinglei,Zhang Hongjie,Lv Xiaoping,Gao Xiang,Zhang Hu,Su Jingling,Feng Baisui,Zhao Ye,Zhu Liangru,Chen Yan,Zhu Lanxiang,Chen Chunxiao,Wang Yali,Wang Yingde,Pang Zhi,Chen Yingxuan,Zhang Xiaolan,Li Hui,Yu Qin,Ye Mei,Zhang Sumin,Tang Wen,Wang Mei,Cao Xiaocang,Zhu Ruixin,Zhou Guangxi,Bian Zhaolian,Guo Xiaofeng,Wu Xiaoli,Liu Jinchun,Xu Wei,Li Yuqin,Guo Qin,Guo Zhiguo,Zhu ShuORCID,Li DalinORCID,Liu JianjunORCID,Ge Tian,Cho JudyORCID,Daly Mark J.,McGovern Dermot P. B.,Ye Byong DukORCID,Song KyuyoungORCID,Kakuta YoichiORCID,Li MingsongORCID,Huang HailiangORCID, , ,

Publisher

Springer Science and Business Media LLC

Subject

Genetics

Reference61 articles.

1. Chaney, A. Fast Facts About GI and Liver Diseases for Nurses (Springer Publishing Company, 2016).

2. GBD 2017 Inflammatory Bowel Disease Collaborators. The global, regional, and national burden of inflammatory bowel disease in 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet Gastroenterol. Hepatol. 5, 17–30 (2020).

3. M’Koma, A. E. Inflammatory bowel disease: an expanding global health problem. Clin. Med. Insights Gastroenterol. 6, 33–47 (2013).

4. de Lange, K. M. et al. Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease. Nat. Genet. 49, 256–261 (2017).

5. Jostins, L. et al. Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. Nature 491, 119–124 (2012).

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