Atlas of group A streptococcal vaccine candidates compiled using large-scale comparative genomics
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Published:2019-05-27
Issue:6
Volume:51
Page:1035-1043
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ISSN:1061-4036
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Container-title:Nature Genetics
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language:en
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Short-container-title:Nat Genet
Author:
Davies Mark R.ORCID, McIntyre Liam, Mutreja Ankur, Lacey Jake A., Lees John A., Towers Rebecca J., Duchêne Sebastián, Smeesters Pierre R., Frost Hannah R.ORCID, Price David J.ORCID, Holden Matthew T. G.ORCID, David Sophia, Giffard Philip M., Worthing Kate A., Seale Anna C., Berkley James A.ORCID, Harris Simon R., Rivera-Hernandez Tania, Berking Olga, Cork Amanda J., Torres Rosângela S. L. A., Lithgow Trevor, Strugnell Richard A.ORCID, Bergmann Rene, Nitsche-Schmitz Patric, Chhatwal Gusharan S., Bentley Stephen D., Fraser John D., Moreland Nicole J., Carapetis Jonathan R., Steer Andrew C., Parkhill JulianORCID, Saul Allan, Williamson Deborah A., Currie Bart J., Tong Steven Y. C., Dougan Gordon, Walker Mark J.ORCID
Publisher
Springer Science and Business Media LLC
Reference79 articles.
1. Carapetis, J. R., Steer, A. C., Mulholland, E. K. & Weber, M. The global burden of group A streptococcal diseases. Lancet Infect. Dis. 5, 685–694 (2005). 2. Walker, M. J. et al. Disease manifestations and pathogenic mechanisms of group A Streptococcus. Clin. Microbiol. Rev. 27, 264–301 (2014). 3. Watkins, D. A. et al. Global, regional, and national burden of rheumatic heart disease, 1990–2015. N. Engl. J. Med. 377, 713–722 (2017). 4. Henningham, A., Gillen, C. M. & Walker, M. J. Group A streptococcal vaccine candidates: potential for the development of a human vaccine. Curr. Top. Microbiol. Immunol. 368, 207–242 (2013). 5. Kotloff, K. L. et al. Safety and immunogenicity of a recombinant multivalent group A streptococcal vaccine in healthy adults: phase 1 trial. J. Am. Med. Assoc. 292, 709–715 (2004).
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