Powerful, scalable and resource-efficient meta-analysis of rare variant associations in large whole genome sequencing studies-Reference-Cited by-同舟云学术

Powerful, scalable and resource-efficient meta-analysis of rare variant associations in large whole genome sequencing studies

Published:2022-12-23 Issue:1 Volume:55 Page:154-164
ISSN:1061-4036
Container-title:Nature Genetics
language:en
Short-container-title:Nat Genet

Author:

Li Xihao^ORCID,Quick Corbin^ORCID,Zhou Hufeng,Gaynor Sheila M.^ORCID,Liu Yaowu,Chen Han,Selvaraj Margaret Sunitha^ORCID,Sun Ryan,Dey Rounak^ORCID,Arnett Donna K.^ORCID,Bielak Lawrence F.^ORCID,Bis Joshua C.,Blangero John^ORCID,Boerwinkle Eric,Bowden Donald W.,Brody Jennifer A.^ORCID,Cade Brian E.^ORCID,Correa Adolfo,Cupples L. Adrienne^ORCID,Curran Joanne E.^ORCID,de Vries Paul S.,Duggirala Ravindranath,Freedman Barry I.^ORCID,Göring Harald H. H.,Guo Xiuqing^ORCID,Haessler Jeffrey,Kalyani Rita R.,Kooperberg Charles^ORCID,Kral Brian G.^ORCID,Lange Leslie A.,Manichaikul Ani,Martin Lisa W.^ORCID,McGarvey Stephen T.^ORCID,Mitchell Braxton D.,Montasser May E.^ORCID,Morrison Alanna C.^ORCID,Naseri Take,O’Connell Jeffrey R.,Palmer Nicholette D.^ORCID,Peyser Patricia A.,Psaty Bruce M.,Raffield Laura M.,Redline Susan,Reiner Alexander P.^ORCID,Reupena Muagututi’a Sefuiva,Rice Kenneth M.^ORCID,Rich Stephen S.^ORCID,Sitlani Colleen M.,Smith Jennifer A.^ORCID,Taylor Kent D.,Vasan Ramachandran S.^ORCID,Willer Cristen J.^ORCID,Wilson James G.,Yanek Lisa R.^ORCID,Zhao Wei^ORCID,Abe Namiko,Abecasis Gonçalo,Aguet Francois,Albert Christine,Almasy Laura,Alonso Alvaro,Ament Seth,Anderson Peter,Anugu Pramod,Applebaum-Bowden Deborah,Ardlie Kristin,Dan Arking ,Ashley-Koch Allison,Aslibekyan Stella,Assimes Tim,Auer Paul,Avramopoulos Dimitrios,Ayas Najib,Balasubramanian Adithya,Barnard John,Barnes Kathleen,Barr R. Graham,Barron-Casella Emily,Barwick Lucas,Beaty Terri,Beck Gerald,Becker Diane,Becker Lewis,Beer Rebecca,Beitelshees Amber,Benjamin Emelia,Benos Takis,Bezerra Marcos,Blackwell Thomas,Blue Nathan,Bowler Russell,Broeckel Ulrich,Broome Jai,Brown Deborah,Bunting Karen,Burchard Esteban,Bustamante Carlos,Buth Erin,Cardwell Jonathan,Carey Vincent,Carrier Julie,Carson April,Carty Cara,Casaburi Richard,Casas Romero Juan P.,Casella James,Castaldi Peter,Chaffin Mark,Chang Christy,Chang Yi-Cheng,Chasman Daniel,Chavan Sameer,Chen Bo-Juen,Chen Wei-Min,Chen Yii-Der Ida,Cho Michael,Choi Seung Hoan,Chuang Lee-Ming,Chung Mina,Chung Ren-Hua,Clish Clary,Comhair Suzy,Conomos Matthew,Cornell Elaine,Crandall Carolyn,Crapo James,Curtis Jeffrey,Custer Brian,Damcott Coleen,Darbar Dawood,David Sean,Davis Colleen,Daya Michelle,de Andrade Mariza,de las Fuentes Lisa,DeBaun Michael,Deka Ranjan,DeMeo Dawn,Devine Scott,Dinh Huyen,Doddapaneni Harsha,Duan Qing,Dugan-Perez Shannon,Durda Jon Peter,Dutcher Susan K.,Eaton Charles,Ekunwe Lynette,El Boueiz Adel,Ellinor Patrick,Emery Leslie,Erzurum Serpil,Farber Charles,Farek Jesse,Fingerlin Tasha,Flickinger Matthew,Fornage Myriam,Franceschini Nora,Frazar Chris,Fu Mao,Fullerton Stephanie M.,Fulton Lucinda,Gabriel Stacey,Gan Weiniu,Gao Shanshan,Gao Yan,Gass Margery,Geiger Heather,Gelb Bruce,Geraci Mark,Germer Soren,Gerszten Robert,Ghosh Auyon,Gibbs Richard,Gignoux Chris,Gladwin Mark,Glahn David,Gogarten Stephanie,Gong Da-Wei,Graw Sharon,Gray Kathryn J.,Grine Daniel,Gross Colin,Gu C. Charles,Guan Yue,Gupta Namrata,Hall Michael,Han Yi,Hanly Patrick,Harris Daniel,Hawley Nicola L.,He Jiang,Ben Heavner ,Heckbert Susan,Hernandez Ryan,Herrington David,Hersh Craig,Hidalgo Bertha,Hixson James,Hobbs Brian,Hokanson John,Hong Elliott,Hoth Karin,Hsiung Chao,Hu Jianhong,Hung Yi-Jen,Huston Haley,Hwu Chii Min,Irvin Marguerite Ryan,Jackson Rebecca,Jain Deepti,Jaquish Cashell,Johnsen Jill,Johnson Andrew,Johnson Craig,Johnston Rich,Jones Kimberly,Kang Hyun Min,Kaplan Robert,Kardia Sharon,Kelly Shannon,Kenny Eimear,Kessler Michael,Khan Alyna,Khan Ziad,Kim Wonji,Kimoff John,Kinney Greg,Konkle Barbara,Kramer Holly,Lange Christoph,Lange Ethan,Laurie Cathy,Laurie Cecelia,LeBoff Meryl,Lee Jiwon,Lee Sandra,Lee Wen-Jane,LeFaive Jonathon,Levine David,Levy Dan,Lewis Joshua,Li Xiaohui,Li Yun,Lin Henry,Lin Honghuang,Liu Simin,Liu Yongmei,Liu Yu,Loos Ruth J. F.,Lubitz Steven,Lunetta Kathryn,Luo James,Magalang Ulysses,Mahaney Michael,Make Barry,Manning Alisa,Manson JoAnn,Marton Melissa,Mathai Susan,Mathias Rasika,May Susanne,McArdle Patrick,McDonald Merry-Lynn,McFarland Sean,McGoldrick Daniel,McHugh Caitlin,McNeil Becky,Mei Hao,Meigs James,Menon Vipin,Mestroni Luisa,Metcalf Ginger,Meyers Deborah A.,Mignot Emmanuel,Mikulla Julie,Min Nancy,Minear Mollie,Minster Ryan L.,Moll Matt,Momin Zeineen,Montgomery Courtney,Muzny Donna,Mychaleckyj Josyf C.,Nadkarni Girish,Naik Rakhi,Nekhai Sergei,Nelson Sarah C.,Neltner Bonnie,Nessner Caitlin,Nickerson Deborah,Nkechinyere Osuji,North Kari,O’Connor Tim,Ochs-Balcom Heather,Okwuonu Geoffrey,Pack Allan,Paik David T.,Pankow James,Papanicolaou George,Parker Cora,Peralta Juan Manuel,Perez Marco,Perry James,Peters Ulrike,Phillips Lawrence S.,Pleiness Jacob,Pollin Toni,Post Wendy,Becker Julia Powers,Boorgula Meher Preethi,Preuss Michael,Qasba Pankaj,Qiao Dandi,Qin Zhaohui,Rafaels Nicholas,Rajendran Mahitha,Rao D. C.,Rasmussen-Torvik Laura,Ratan Aakrosh,Reed Robert,Reeves Catherine,Regan Elizabeth,Robillard Rebecca,Robine Nicolas,Dan Roden ,Roselli Carolina,Ruczinski Ingo,Runnels Alexi,Russell Pamela,Ruuska Sarah,Ryan Kathleen,Sabino Ester Cerdeira,Saleheen Danish,Salimi Shabnam,Salvi Sejal,Salzberg Steven,Sandow Kevin,Sankaran Vijay G.,Santibanez Jireh,Schwander Karen,Schwartz David,Sciurba Frank,Seidman Christine,Seidman Jonathan,Sériès Frédéric,Sheehan Vivien,Sherman Stephanie L.,Shetty Amol,Shetty Aniket,Sheu Wayne Hui-Heng,Shoemaker M. Benjamin,Silver Brian,Silverman Edwin,Skomro Robert,Smith Albert Vernon,Smith Josh,Smith Nicholas,Smith Tanja,Smoller Sylvia,Snively Beverly,Snyder Michael,Sofer Tamar,Sotoodehnia Nona,Stilp Adrienne M.,Storm Garrett,Streeten Elizabeth,Su Jessica Lasky,Sung Yun Ju,Sylvia Jody,Szpiro Adam,Taliun Daniel,Tang Hua,Taub Margaret,Taylor Matthew,Taylor Simeon,Telen Marilyn,Thornton Timothy A.,Threlkeld Machiko,Tinker Lesley,Tirschwell David,Tishkoff Sarah,Tiwari Hemant,Tong Catherine,Tracy Russell,Tsai Michael,Vaidya Dhananjay,Van Den Berg David,VandeHaar Peter,Vrieze Scott,Walker Tarik,Wallace Robert,Walts Avram,Wang Fei Fei,Wang Heming,Wang Jiongming,Watson Karol,Watt Jennifer,Weeks Daniel E.,Weinstock Joshua,Weir Bruce,Weiss Scott T.,Weng Lu-Chen,Wessel Jennifer,Williams Kayleen,Williams L. Keoki,Wilson Carla,Winterkorn Lara,Wong Quenna,Wu Joseph,Xu Huichun,Yang Ivana,Yu Ketian,Zekavat Seyedeh Maryam,Zhang Yingze,Zhao Snow Xueyan,Zhu Xiaofeng,Ziv Elad,Zody Michael,Zoellner Sebastian,Rotter Jerome I.,Natarajan Pradeep,Peloso Gina M.^ORCID,Li Zilin^ORCID,Lin Xihong^ORCID,

Funder

U.S. Department of Health & Human Services | NIH | National Cancer Institute

U.S. Department of Health & Human Services | NIH | National Human Genome Research Institute

U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute

U.S. Department of Health & Human Services | NIH | National Institute of Diabetes and Digestive and Kidney Diseases

U.S. Department of Health & Human Services | NIH | National Institute of Mental Health

U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke

U.S. Department of Health & Human Services | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases

U.S. Department of Health & Human Services | NIH | National Institute on Aging

U.S. Department of Health & Human Services | NIH | National Center for Research Resources

The American Diabetes Association

U.S. Department of Health & Human Services | National Institutes of Health

American Heart Association

U.S. Department of Health & Human Services | NIH | National Center for Advancing Translational Sciences

The Evans Medical Foundation and the Jay and Louis Coffman Endowment from the Department of Medicine, Boston University School of Medicine

U.S. Department of Health & Human Services | NIH | National Institute of Nursing Research

Publisher

Springer Science and Business Media LLC

Subject

Genetics

Link

https://www.nature.com/articles/s41588-022-01225-6.pdf

Reference55 articles.

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4. Hindy, G. et al. Rare coding variants in 35 genes associate with circulating lipid levels—a multi-ancestry analysis of 170,000 exomes. Am. J. Hum. Genet. 109, 81–96 (2022).

5. Flannick, J. et al. Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls. Nature 570, 71–76 (2019).

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