VX-680, a potent and selective small-molecule inhibitor of the Aurora kinases, suppresses tumor growth in vivo-Reference-Cited by-同舟云学术

VX-680, a potent and selective small-molecule inhibitor of the Aurora kinases, suppresses tumor growth in vivo

Published:2004-02-22 Issue:3 Volume:10 Page:262-267
ISSN:1078-8956
Container-title:Nature Medicine
language:en
Short-container-title:Nat Med

Author:

Harrington Elizabeth A,Bebbington David,Moore Jeff,Rasmussen Richele K,Ajose-Adeogun Abi O,Nakayama Tomoko,Graham Joanne A,Demur Cecile,Hercend Thierry,Diu-Hercend Anita,Su Michael,Golec Julian M C,Miller Karen M

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

http://www.nature.com/articles/nm1003.pdf

Reference46 articles.

1. Carmena, M. & Earnshaw, W.C. The cellular geography of Aurora kinases. Nat. Rev. Mol. Biol. 4, 842–854 (2003).

2. Bischoff, J.R. & Plowman, G.D. The Aurora/Ipl1p kinase family: regulators of chromosome segregation and cytokinesis. Trends Cell Biol. 9, 454–459 (1999).

3. Giet, R. & Prigent, C. Aurora/Ipl1p-related kinases, a new oncogenic family of mitotic serine-threonine kinases. J. Cell Sci. 112, 3591–3601 (1999).

4. Nigg, E.A. Mitotic kinases as regulators of cell division and its checkpoints. Nat. Rev. Mol. Cell Biol. 2, 21–32 (2001).

5. Adams, R.R., Carmena, M. & Earnshaw, W.C. Chromosomal passengers and the (aurora) ABCs of mitosis. Trends Cell Biol. 11, 49–54 (2001).

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