THEMIS enhances TCR signaling and enables positive selection by selective inhibition of the phosphatase SHP-1-Reference-Cited by-同舟云学术

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THEMIS enhances TCR signaling and enables positive selection by selective inhibition of the phosphatase SHP-1

Published:2017-02-27 Issue:4 Volume:18 Page:433-441
ISSN:1529-2908
Container-title:Nature Immunology
language:en
Short-container-title:Nat Immunol

Author:

Choi Seeyoung,Warzecha Claude,Zvezdova Ekaterina,Lee Jan,Argenty Jérémy,Lesourne Renaud,Aravind L,Love Paul E

Publisher

Springer Science and Business Media LLC

Subject

Immunology,Immunology and Allergy

Link

http://www.nature.com/articles/ni.3692.pdf

Reference49 articles.

1. Koch, U. & Radtke, F. Mechanisms of T cell development and transformation. Annu. Rev. Cell Dev. Biol. 27, 539–562 (2011).

2. Aifantis, I., Mandal, M., Sawai, K., Ferrando, A. & Vilimas, T. Regulation of T-cell progenitor survival and cell-cycle entry by the pre-T-cell receptor. Immunol. Rev. 209, 159–169 (2006).

3. Starr, T.K., Jameson, S.C. & Hogquist, K.A. Positive and negative selection of T cells. Annu. Rev. Immunol. 21, 139–176 (2003).

4. Hogquist, K.A. & Jameson, S.C. The self-obsession of T cells: how TCR signaling thresholds affect fate 'decisions' and effector function. Nat. Immunol. 15, 815–823 (2014).

5. Brownlie, R.J. & Zamoyska, R. T cell receptor signalling networks: branched, diversified and bounded. Nat. Rev. Immunol. 13, 257–269 (2013).

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1. A mutation in Themis contributes to anaphylaxis severity following oral peanut challenge in CC027 mice;Journal of Allergy and Clinical Immunology;2024-08

2. Adjusting to self in the thymus: CD4 versus CD8 lineage commitment and regulatory T cell development;Journal of Experimental Medicine;2024-07-09

3. THEMIS promotes T cell development and maintenance by rising the signaling threshold of the inhibitory receptor BTLA;Proceedings of the National Academy of Sciences;2024-05-07

4. Positive regulation of Vav1 by Themis controls CD4 T cell pathogenicity in a mouse model of central nervous system inflammation;Cellular and Molecular Life Sciences;2024-04-02

5. Signaling via a CD27-TRAF2-SHP-1 axis during naive T cell activation promotes memory-associated gene regulatory networks;Immunity;2024-02

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