A prospective biomarker analysis of alvocidib followed by cytarabine and mitoxantrone in MCL-1-dependent relapsed/refractory acute myeloid leukemia
Author:
Funder
Sumitomo Dainippon Pharma Oncology, Lehi, UT
Publisher
Springer Science and Business Media LLC
Subject
Oncology,Hematology
Link
https://www.nature.com/articles/s41408-021-00568-3.pdf
Reference14 articles.
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2. Adams KW, Cooper GM. Rapid turnover of mcl-1 couples translation to cell survival and apoptosis. J Biol Chem. 2007;282:6192–200.
3. Zeidner JF, Karp JE. Clinical activity of alvocidib (flavopiridol) in acute myeloid leukemia. Leuk Res. 2015;39:1312–8.
4. Zeidner JF, Lee DJ, Frattini M, Fine GD, Costas J, Kolibaba K, et al. Phase I study of alvocidib followed by 7+3 (cytarabine + daunorubicin) in newly diagnosed acute myeloid leukemia. Clin Cancer Res. 2021;27:60–9.
5. Davidson A, Hinkely, DV. Bootstrap methods and their application. Cambridge: Cambridge University Press; 1997.
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