Phase I study of alvocidib plus cytarabine/mitoxantrone or cytarabine/daunorubicin for acute myeloid leukemia in Japan

Author:

Ikezoe Takayuki1,Ando Kiyoshi2,Onozawa Masahiro3,Yamane Takahisa4,Hosono Naoko5,Morita Yasuyoshi6,Kiguchi Toru7,Iwasaki Hiromi8,Miyamoto Toshihiro9ORCID,Matsubara Keisuke10,Sugimoto Saori10,Miyazaki Yasushi11ORCID,Kizaki Masahiro12,Akashi Koichi9

Affiliation:

1. Department of Hematology Fukushima Medical University Hospital Fukushima Japan

2. Department of Hematology and Oncology Tokai University Tokyo Japan

3. Department of Hematology Hokkaido University Hospital Sapporo Japan

4. Department of Hematology Osaka City General Hospital Osaka Japan

5. Department of Hematology and Oncology University of Fukui Hospital Fukui Japan

6. Department of Hematology and Rheumatology Kindai University Hospital Osaka‐Sayama Japan

7. Department of Hematology Chugoku Central Hospital Fukuyama Japan

8. Department of Hematology, National Hospital Organization Kyushu Medical Center Fukuoka Japan

9. Department of Medicine and Biosystemic Science Faculty of Medicine Kyushu University Fukuoka Japan

10. Sumitomo Pharma Co., Ltd. Tokyo Japan

11. Department of Hematology, Atomic Bomb Disease and Hibakusha Medicine Unit, Atomic Bomb Disease Institute Nagasaki University Nagasaki Japan

12. Department of Hematology, Saitama Medical Center Saitama Medical University Saitama Japan

Funder

Dainippon Sumitomo Pharma

Publisher

Wiley

Subject

Cancer Research,Oncology,General Medicine

Reference20 articles.

1. ‘Acute myeloid leukemia: a comprehensive review and 2016 update’

2. International Agency for Research on Cancer.Globocan Factsheet 2020: Japan.https://gco.iarc.fr/today/data/factsheets/populations/392‐japan‐fact‐sheets.pdf. Accessed October 30 2021.

3. Type distribution of myeloid leukemia from Cancer Incidence in Five Continents Vol. X

4. National Comprehensive Cancer Network.NCCN clinical practice guidelines in oncology: Acute myeloid leukemia. Version 3.2021.https://www.nccn.org/professionals/physician_gls/pdf/aml.pdf. Accessed October 30 2021.

5. Salvage regimens using conventional chemotherapy agents for relapsed/refractory adult AML patients: a systematic literature review

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