Assessment of AAV9 distribution and transduction in rats after administration through Intrastriatal, Intracisterna magna and Lumbar Intrathecal routes-Reference-Cited by-同舟云学术

Assessment of AAV9 distribution and transduction in rats after administration through Intrastriatal, Intracisterna magna and Lumbar Intrathecal routes

Published:2022-05-30 Issue:1-2 Volume:30 Page:132-141
ISSN:0969-7128
Container-title:Gene Therapy
language:en
Short-container-title:Gene Ther

Author:

Chandran Jayanth,Chowdhury Ekram Ahmed,Perkinton Michael,Jamier Tanguy^ORCID,Sutton Daniel,Wu Shengjia,Dobson Claire,Shah Dhaval K.,Chessell Iain,Meno-Tetang Guy M. L.^ORCID

Funder

AstraZeneca

Publisher

Springer Science and Business Media LLC

Subject

Genetics,Molecular Biology,Molecular Medicine

Link

https://www.nature.com/articles/s41434-022-00346-1.pdf

Reference45 articles.

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2. Merkel SF, Andrews AM, Lutton EM, Mu D, Hudry E, Hyman BT, et al. Trafficking of adeno-associated virus vectors across a model of the blood-brain barrier; a comparative study of transcytosis and transduction using primary human brain endothelial cells. J Neurochem. 2017;140:216–30.

3. Bailey RM, Rozenberg A, Gray SJ. Comparison of high-dose intracisterna magna and lumbar puncture intrathecal delivery of AAV9 in mice to treat neuropathies. Brain Res. 2020;1739:146832.