New clinical trials in CUP and a novel paradigm in cancer classification
Author:
Publisher
Springer Science and Business Media LLC
Link
https://www.nature.com/articles/s41571-024-00942-7.pdf
Reference10 articles.
1. André, F., Rassy, E., Marabelle, A., Michiels, S. & Besse, B. Forget lung, breast or prostate cancer: why tumour naming needs to change. Nature 626, 26–29 (2024).
2. Liu, X. et al. Site-specific therapy guided by a 90-gene expression assay versus empirical chemotherapy in patients with cancer of unknown primary (Fudan CUP-001): a randomised controlled trial. Lancet Oncol 25, 1092–1102 (2024).
3. Krämer, A. et al. Molecularly guided therapy versus chemotherapy after disease control in unfavourable cancer of unknown primary (CUPISCO): an open-label, randomised, phase 2 study. Lancet 404, 527–539 (2024).
4. Pavlidis, N. & Pentheroudakis, G. Cancer of unknown primary site. Lancet 379, 1428–1435 (2012).
5. Hayashi, H. et al. Randomized phase II trial comparing site-specific treatment based on gene expression profiling with carboplatin and paclitaxel for patients with cancer of unknown primary site. J. Clin. Oncol 37, 570–579 (2019).
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