N-glycosylation bidirectionally extends the boundaries of thymocyte positive selection by decoupling Lck from Ca2+ signaling-Reference-Cited by-同舟云学术

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N-glycosylation bidirectionally extends the boundaries of thymocyte positive selection by decoupling Lck from Ca2+ signaling

Published:2014-09-28 Issue:11 Volume:15 Page:1038-1045
ISSN:1529-2908
Container-title:Nature Immunology
language:en
Short-container-title:Nat Immunol

Author:

Zhou Raymond W,Mkhikian Haik,Grigorian Ani,Hong Amanda,Chen David,Arakelyan Araz,Demetriou Michael

Publisher

Springer Science and Business Media LLC

Subject

Immunology,Immunology and Allergy

Link

http://www.nature.com/articles/ni.3007.pdf

Reference48 articles.

1. Starr, T.K., Jameson, S.C. & Hogquist, K.A. Positive and negative selection of T cells. Annu. Rev. Immunol. 21, 139–176 (2003).

2. Morris, G.P. & Allen, P.M. How the TCR balances sensitivity and specificity for the recognition of self and pathogens. Nat. Immunol. 13, 121–128 (2012).

3. Gallo, E.M. et al. Calcineurin sets the bandwidth for discrimination of signals during thymocyte development. Nature 450, 731–735 (2007).

4. Parsons, S.A. et al. Genetic loss of calcineurin blocks mechanical overload-induced skeletal muscle fiber type switching but not hypertrophy. J. Biol. Chem. 279, 26192–26200 (2004).

5. Li, Q.J. et al. miR-181a is an intrinsic modulator of T cell sensitivity and selection. Cell 129, 147–161 (2007).

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