How the TCR balances sensitivity and specificity for the recognition of self and pathogens
Author:
Publisher
Springer Science and Business Media LLC
Subject
Immunology,Immunology and Allergy
Link
http://www.nature.com/articles/ni.2190.pdf
Reference118 articles.
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3. Hogquist, K.A. et al. Identification of a naturally occurring ligand for thymic positive selection. Immunity 6, 389–399 (1997).
4. Hu, Q. et al. Specific recognition of thymic self-peptides induces the positive selection of cytotoxic T lymphocytes. Immunity 7, 221–231 (1997).
5. Lo, W.L. et al. An endogenous peptide positively selects and augments the activation and survival of peripheral CD4+ T cells. Nat. Immunol. 10, 1155–1161 (2009).
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