Targeted Perturb-seq enables genome-scale genetic screens in single cells-Reference-Cited by-同舟云学术

Targeted Perturb-seq enables genome-scale genetic screens in single cells

Published:2020-06 Issue:6 Volume:17 Page:629-635
ISSN:1548-7091
Container-title:Nature Methods
language:en
Short-container-title:Nat Methods

Author:

Schraivogel Daniel^ORCID,Gschwind Andreas R.^ORCID,Milbank Jennifer H.,Leonce Daniel R.,Jakob Petra,Mathur Lukas,Korbel Jan O.^ORCID,Merten Christoph A.,Velten Lars^ORCID,Steinmetz Lars M.^ORCID

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Molecular Biology,Biochemistry,Biotechnology

Link

http://www.nature.com/articles/s41592-020-0837-5.pdf

Reference55 articles.

1. Steinmetz, L. M. et al. Systematic screen for human disease genes in yeast. Nat. Genet. 31, 400–404 (2002).

2. Winzeler, E. A. et al. Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis. Science 285, 901–906 (1999).

3. Shifrut, E. et al. Genome-wide CRISPR screens in primary human T cells reveal key regulators of immune function. Cell 175, 1958–1971.e15 (2018).

4. Dixit, A. et al. Perturb-Seq: dissecting molecular circuits with scalable single-cell RNA profiling of pooled genetic screens. Cell 167, 1853–1866.e17 (2016).

5. Jaitin, D. A. et al. Dissecting immune circuits by linking CRISPR-pooled screens with single-cell RNA-seq. Cell 167, 1883–1896.e15 (2016).

Cited by 164 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. A mini-review on perturbation modelling across single-cell omic modalities;Computational and Structural Biotechnology Journal;2024-12

2. PerturbDB for unraveling gene functions and regulatory networks;Nucleic Acids Research;2024-09-11

3. Deciphering the impact of genomic variation on function;Nature;2024-09-04

4. Guide assignment in single-cell CRISPR screens using crispat;Bioinformatics;2024-09

5. Design of microbial catalysts for two-stage processes;Nature Reviews Bioengineering;2024-08-22