Pironetin reacts covalently with cysteine-316 of α-tubulin to destabilize microtubule-Reference-Cited by-同舟云学术

Pironetin reacts covalently with cysteine-316 of α-tubulin to destabilize microtubule

Published:2016-06-30 Issue:1 Volume:7 Page:
ISSN:2041-1723
Container-title:Nature Communications
language:en
Short-container-title:Nat Commun

Author:

Yang Jianhong,Wang Yuxi,Wang Taijing,Jiang Jian^ORCID,Botting Catherine H.,Liu Huanting,Chen Qiang^ORCID,Yang Jinliang,Naismith James H.,Zhu Xiaofeng,Chen Lijuan

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

Link

http://www.nature.com/articles/ncomms12103.pdf

Reference42 articles.

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4. Kavallaris, M. Microtubules and resistance to tubulin-binding agents. Nat. Rev. Cancer 10, 194–204 (2010).

5. Nogales, E., Wolf, S. G., Khan, I. A., Luduena, R. F. & Downing, K. H. Structure of tubulin at 6.5 Å and location of the taxol-binding site. Nature 375, 424–427 (1995).

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