VCP recruitment to mitochondria causes mitophagy impairment and neurodegeneration in models of Huntington’s disease
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry
Link
http://www.nature.com/articles/ncomms12646.pdf
Reference68 articles.
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3. Costa, V. & Scorrano, L. Shaping the role of mitochondria in the pathogenesis of Huntington's disease. EMBO J. 31, 1853–1864 (2012).
4. Bossy-Wetzel, E., Petrilli, A. & Knott, A. B. Mutant huntingtin and mitochondrial dysfunction. Trends Neurosci. 31, 609–616 (2008).
5. Guo, X. et al. Inhibition of mitochondrial fragmentation diminishes Huntington's disease-associated neurodegeneration. J. Clin. Invest. 123, 5371–5388 (2013).
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