Translocator protein (18 kDa) (TSPO) as a therapeutic target for neurological and psychiatric disorders-Reference-Cited by-同舟云学术

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Translocator protein (18 kDa) (TSPO) as a therapeutic target for neurological and psychiatric disorders

Published:2010-12 Issue:12 Volume:9 Page:971-988
ISSN:1474-1776
Container-title:Nature Reviews Drug Discovery
language:en
Short-container-title:Nat Rev Drug Discov

Author:

Rupprecht Rainer,Papadopoulos Vassilios,Rammes Gerhard,Baghai Thomas C.,Fan Jinjiang,Akula Nagaraju,Groyer Ghislaine,Adams David,Schumacher Michael

Publisher

Springer Science and Business Media LLC

Subject

Drug Discovery,Pharmacology,General Medicine

Link

http://www.nature.com/articles/nrd3295.pdf

Reference207 articles.

1. Papadopoulos, V. et al. Translocator protein (18kDa): new nomenclature for the peripheral-type benzodiazepine receptor based on its structure and molecular function. Trends Pharmacol. Sci. 27, 402–409 (2006).

2. Papadopoulos, V., Liu, J. & Culty, M. Is there a mitochondrial signaling complex facilitating cholesterol import? Mol. Cell Endocrinol. 266, 59–64 (2007).

3. Jorda, E. G. et al. Evidence in favour of a role for peripheral-type benzodiazepine receptor ligands in amplification of neuronal apoptosis. Apoptosis 10, 91–104 (2005).

4. Jayakumar, A. R., Panickar, K. S. & Norenberg, M. D. Effects on free radical generation by ligands of the peripheral benzodiazepine receptor in cultured neural cells. J. Neurochem. 83, 1226–1234 (2002).

5. Delavoie, F. et al. In vivo and in vitro peripheral-type benzodiazepine receptor polymerization: functional significance in drug ligand and cholesterol binding. Biochemistry 42, 4506–4519 (2003).

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1. 18 kDa Translocator protein (TSPO) is upregulated in rat brain after peripheral nerve injury and downregulated by diroximel fumarate;Brain, Behavior, and Immunity;2025-01

2. The mitochondrial TSPO ligand Atriol mitigates metabolic-associated steatohepatitis by downregulating CXCL1;Metabolism;2024-10

3. Neurobiological mechanisms in the kynurenine pathway and major depressive disorder;Reviews in the Neurosciences;2024-09-09

4. TSPO in pancreatic beta cells and its possible involvement in type 2 diabetes;Biochimie;2024-09

5. Structure-based drug design for TSPO: Challenges and opportunities;Biochimie;2024-09

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