The mitochondrial TSPO ligand Atriol mitigates metabolic-associated steatohepatitis by downregulating CXCL1

Author:

Li Yuchang,Chen Liting,Sottas Chantal,Raul Mahima Chandrakant,Patel Nrupa Dinesh,Bijja Janaki Ramulu,Ahmed S. Kaleem,Kapelanski-Lamoureux Audrey,Lazaris Anthoula,Metrakos Peter,Zambidis Alexander,Chopra Shefali,Li Meng,Sugahara Go,Saito Takeshi,Papadopoulos Vassilios

Funder

USC Alfred E Mann School of Pharmacy and Pharmaceutical Sciences

University of South China

NIH

Publisher

Elsevier BV

Reference50 articles.

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2. Non-alcoholic steatohepatitis pathogenesis: sublethal hepatocyte injury as a driver of liver inflammation;Ibrahim;Gut,2018

3. A phase 3, randomized, controlled trial of Resmetirom in NASH with liver fibrosis;Harrison;N Engl J Med,2024

4. Mechanisms of NAFLD development and therapeutic strategies;Friedman;Nat Med,2018

5. New targets for NAFLD;Parlati;JHEP Rep,2021

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