Evidence for an active transport of morphine-6-β-d-glucuronide but not P-glycoprotein-mediated at the blood-brain barrier-Reference-Cited by-同舟云学术

Evidence for an active transport of morphine-6-β-d-glucuronide but not P-glycoprotein-mediated at the blood-brain barrier

Published:2003-08-29 Issue:6 Volume:86 Page:1564-1567
ISSN:0022-3042
Container-title:Journal of Neurochemistry
language:en
Short-container-title:

Author:

Bourasset Fanchon,Cisternino Salvatore,Temsamani Jamal,Scherrmann Jean-Michel

Publisher

Wiley

Subject

Cellular and Molecular Neuroscience,Biochemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1046/j.1471-4159.2003.01990.x/fullpdf

Reference38 articles.

1. Morphine-6-glucuronide: analgesic effects and receptor binding profile in rats;Abbott;Life Sci.,1988

2. Poor permeability of morphine 3-glucuronide and morphine 6-glucuronide through the blood-brain barrier in the rat;Bickel;J. Pharmacol. Exp. Ther.,1996

3. A family of drug transporters: the multidrug resistance-associated proteins;Borst;J. Natl Cancer Inst.,2000

4. Blood-brain barrier transport and brain distribution of morphine-6-glucuronide in relation to the antinociceptive effect in rats - pharmacokinetic/pharmacodynamic modelling;Bouw;Br. J. Pharmacol.,2001

5. Morphine-6-glucuronide has high affinity for the opioid receptor;Christensen;Pharmacol. Toxicol.,1987

Cited by 103 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. The role of drug efflux and uptake transporters in the plasma pharmacokinetics and tissue disposition of morphine and its main metabolites;Toxicology and Applied Pharmacology;2024-09

2. The Active Glucuronide Metabolite of the Brain Protectant IMM-H004 with Poor Blood–Brain Barrier Permeability Demonstrates a High Partition in the Rat Brain via Multiple Mechanisms;Pharmaceutics;2024-02-27

3. Does nonlinear blood-brain barrier transport matter for (lower) morphine dosing strategies?;European Journal of Pharmaceutical Sciences;2023-08

4. Peripheralization Strategies Applied to Morphinans and Implications for Improved Treatment of Pain;Molecules;2023-06-14

5. Heroin and its metabolites: relevance to heroin use disorder;Translational Psychiatry;2023-04-08