Human DNA polymerase‐η, an A‐T mutator in somatic hypermutation of rearranged immunoglobulin genes, is a reverse transcriptase-Reference-Cited by-同舟云学术

Human DNA polymerase‐η, an A‐T mutator in somatic hypermutation of rearranged immunoglobulin genes, is a reverse transcriptase

Published:2004-04 Issue:2 Volume:82 Page:219-225
ISSN:0818-9641
Container-title:Immunology & Cell Biology
language:en
Short-container-title:Immunol Cell Biol

Author:

Franklin Andrew¹,Milburn Peter J²,Blanden Robert V¹,Steele Edward J¹

Affiliation:

1. Division of Immunology and Genetics, John Curtin School of Medical Research, Australian National University GPO Box 334 Canberra ACT 2601 Australia

2. Biomolecular Resource Facility, John Curtin School of Medical Research, Australian National University GPO Box 334 Canberra ACT 2601 Australia

Publisher

Wiley

Subject

Cell Biology,Immunology,Immunology and Allergy

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1046/j.0818-9641.2004.01221.x

Reference68 articles.

1. Class Switch Recombination and Hypermutation Require Activation-Induced Cytidine Deaminase (AID), a Potential RNA Editing Enzyme

2. Activation-Induced Cytidine Deaminase (AID) Deficiency Causes the Autosomal Recessive Form of the Hyper-IgM Syndrome (HIGM2)

3. AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification

4. Altering the pathway of immunoglobulin hypermutation by inhibiting uracil-DNA glycosylase

5. Origin of Antibody Variation

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