Activating point mutations in the βC chain of the GM-CSF, IL-3 and IL-5 receptors are not a major contributory factor in the pathogenesis of acute myeloid leukaemia
Author:
Publisher
Wiley
Subject
Hematology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1046/j.1365-2141.1998.00939.x/fullpdf
Reference35 articles.
1. Point mutations within a dimer interface homology domain of the c-MPL induce constitutive receptor activity and tumorigenicity;Alexander;EMBO Journal,1995
2. Human GM-CSF receptor α-chain gene is highly polymorphic but not rearranged in AML;Bardy;Leukemia,1992
3. Mutations of the granulocyte-colony stimulating factor receptor in patients with severe congenital neutropenia are not required for transformation to acute myeloid leukaemia and may be a bystander phenomenon;Bernard;British Journal of Haematology,1998
4. Analysis of granulocyte colony stimulating factor receptor isoforms, polymorphisms and mutations in normal haemopoietic cells and acute myeloid leukaemia blasts;Bernard;British Journal of Haematology,1996
5. Structure and expression of the GM-CSF receptor α and β chain genes in human leukemia;Brown;Leukemia,1993
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