Involvement of cytochrome P450 2C9, 2E1 and 3A4 in trimethadione N-demethylation in human microsomes

Author:

Tanaka E.,Kurata N.,Yasuhara H.

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference8 articles.

1. Pharmacokinetic studies of trimethadione and its metabolite in rats with chemical-induced live injury;Tanaka;Journal of Pharmacobiodynamics,1981

2. Trimethadione metabolism as a probe drug to estimate hepatic oxidizing capacity in rats;Tanaka;Comparative Biochemistry and Physiology C,1993

3. Trimethadione as a probe drug to estimate hepatic oxidizing capacity in humans;Tanaka;Comparative Biochemistry and Physiology C,1996

4. Simplified approach for determination of hepatic drug-oxidizing capacity using trimethadione metabolism as an indicator;Tanaka;Biopharmaceutics and Drug Disposition,1989

5. Trimethadione metabolism, a useful indicator for assessing hepatic drug-oxidizing capacity;Nakamura;Biochemical Pharmacology,1994

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