Involvement of cytochrome P450 2C9, 2E1 and 3A4 in trimethadione N-demethylation in human microsomes
Author:
Publisher
Wiley
Subject
Pharmacology (medical),Pharmacology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1046/j.1365-2710.2003.00524.x/fullpdf
Reference8 articles.
1. Pharmacokinetic studies of trimethadione and its metabolite in rats with chemical-induced live injury;Tanaka;Journal of Pharmacobiodynamics,1981
2. Trimethadione metabolism as a probe drug to estimate hepatic oxidizing capacity in rats;Tanaka;Comparative Biochemistry and Physiology C,1993
3. Trimethadione as a probe drug to estimate hepatic oxidizing capacity in humans;Tanaka;Comparative Biochemistry and Physiology C,1996
4. Simplified approach for determination of hepatic drug-oxidizing capacity using trimethadione metabolism as an indicator;Tanaka;Biopharmaceutics and Drug Disposition,1989
5. Trimethadione metabolism, a useful indicator for assessing hepatic drug-oxidizing capacity;Nakamura;Biochemical Pharmacology,1994
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