The Application and Mechanism of Action of Ribavirin in Therapy of Hepatitis C-Reference-Cited by-同舟云学术

The Application and Mechanism of Action of Ribavirin in Therapy of Hepatitis C

Published:2012-08 Issue:1 Volume:23 Page:1-12
ISSN:2040-2066
Container-title:Antiviral Chemistry and Chemotherapy
language:en
Short-container-title:Antivir Chem Chemother

Author:

Thomas Emmanuel¹²,Ghany Marc G¹,Liang T Jake¹

Affiliation:

1. Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, MD, USA

2. Schiff Center For Liver Diseases, University of Miami Miller School of Medicine, Miami, FL, USA

Abstract

Ribavirin has been used as an antiviral agent for several decades. Although it has activity against numerous viruses, its major use clinically has been in the treatment of respiratory syncytial virus in paediatric patients and chronic HCV infection in both children and adults. This review highlights the clinical application and mechanism of action of ribavirin and discusses the future role of ribavirin in treatment of HCV where there are intense research efforts to improve therapy.

Publisher

SAGE Publications

Link

http://journals.sagepub.com/doi/pdf/10.3851/IMP2125

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