A Pharmacological Update of Triazole Derivative: A Review

Abstract

Abstract: Recently, a large number of novel heterocyclic compounds and their derivatives have been synthesized, and studies on their biological functions have been conducted. Even though the triazole moiety of this scaffold appears to be fairly small, many researchers are interested in it be-cause of its biological profile and variety of potential uses. Triazole derivatives have been synthe-sized and published by various researchers as their important characteristic against various dis-eases. Several researchers are interested in this scaffold because of its biological profile and wide variety of potential uses, even if its triazole moiety seems to be somewhat less. The derivative of this heterocyclic ring produced various biological activities such as anti-inflammatory, anticon-vulsant, hypoglycemic, antitubercular, anxiolytic, antimicrobial, antitumor, and anticancer. The current review article focuses on pharmacological profile associated with triazoles and mainly fo-cuses on structural modification done for various targets, along with a brief description of targets.