CYP3A4 Induction in the Liver and Intestine of Pregnane X Receptor/CYP3A-Humanized Mice: Approaches by Mass Spectrometry Imaging and Portal Blood Analysis-Reference-Cited by-同舟云学术

CYP3A4 Induction in the Liver and Intestine of Pregnane X Receptor/CYP3A-Humanized Mice: Approaches by Mass Spectrometry Imaging and Portal Blood Analysis

Published:2019-08-27 Issue:5 Volume:96 Page:600-608
ISSN:0026-895X
Container-title:Molecular Pharmacology
language:en
Short-container-title:Mol Pharmacol

Author:

Kobayashi Kaoru,Kuze Jiro,Abe Satoshi,Takehara Shoko,Minegishi Genki,Igarashi Katsuhide,Kitajima Satoshi,Kanno Jun,Yamamoto Takushi,Oshimura Mitsuo,Kazuki Yasuhiro

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmacology,Molecular Medicine

Reference26 articles.

1. Modification of single-nucleotide polymorphism in a fully humanized CYP3A mouse by genome editing technology;Abe;Sci Rep,2017

2. SXR, a novel steroid and xenobioticsensing nuclear receptor

3. The Induction of Cytochrome P450 3A5 (CYP3A5) in the Human Liver and Intestine Is Mediated by the Xenobiotic Sensors Pregnane X Receptor (PXR) and Constitutively Activated Receptor (CAR)

4. Growth Hormone Determines Sexual Dimorphism of Hepatic Cytochrome P450 3A4 Expression in Transgenic Mice

5. The Orphan Human Pregnane X Receptor Mediates the Transcriptional Activation ofCYP3A4by Rifampicin through a Distal Enhancer Module

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