Modification of single-nucleotide polymorphism in a fully humanized CYP3A mouse by genome editing technology
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-017-15033-0.pdf
Reference36 articles.
1. Martignoni, M., Groothuis, G. M. & de Kanter, R. Species differences between mouse, rat, dog, monkey and human CYP-mediated drug metabolism, inhibition and induction. Expert Opin. Drug Metab Toxicol 2, 875–894 (2006).
2. Kazuki, Y. et al. Trans-chromosomic mice containing a human CYP3A cluster for prediction of xenobiotic metabolism in humans. Hum Mol Genet 22, 578–592 (2013).
3. Kazuki, Y. et al. Thalidomide-induced limb abnormalities in a humanized CYP3A mouse model. Sci Rep 6, 21419 (2016).
4. Kobayashi, K. et al. Gender difference of hepatic and intestinal CYP3A4 in CYP3A-humanized mice generated by a human chromosome-engineering technique. Drug Metab Lett, https://doi.org/10.2174/1872312811666170404153804, (2017).
5. Takiguchi, M. et al. A novel and stable mouse artificial chromosome vector. ACS Synth Biol 3, 903–914 (2014).
Cited by 25 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Vincristine Disposition and Neurotoxicity Are Unchanged in Humanized CYP3A5 Mice;Drug Metabolism and Disposition;2023-12-08
2. Predictability of human exposure by human‐CYP3A4‐transgenic mouse models: A meta‐analysis;Clinical and Translational Science;2023-12
3. Metabolic Disposition of Triazolam and Clobazam in Humanized CYP3A Mice with a Double-Knockout Background of MouseCyp2candCyp3aGenes;Drug Metabolism and Disposition;2022-11-15
4. Prenatal ethanol exposure induces dynamic changes of expression and activity of hepatic cytochrome P450 isoforms in male rat offspring;Reproductive Toxicology;2022-04
5. Panel of human cell lines with human/mouse artificial chromosomes;Scientific Reports;2022-02-22
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3