Biotransformation of Daclatasvir In Vitro and in Nonclinical Species: Formation of the Main Metabolite by Pyrrolidine -Oxidation and Rearrangement-Reference-Cited by-同舟云学术

Biotransformation of Daclatasvir In Vitro and in Nonclinical Species: Formation of the Main Metabolite by Pyrrolidine -Oxidation and Rearrangement

Published:2016-03-30 Issue:6 Volume:44 Page:809-820
ISSN:1521-009X
Container-title:Drug Metabolism and Disposition
language:en
Short-container-title:Drug Metabolism and Disposition

Author:

Li W.,Zhao W.,Liu X.,Huang X.,Lopez O. D.,Leet J. E.,Fancher R. M.,Nguyen V.,Goodrich J.,Easter J.,Hong Y.,Caceres-Cortes J.,Chang S. Y.,Ma L.,Belema M.,Hamann L. G.,Gao M.,Zhu M.,Shu Y.-Z.,Humphreys W. G.,Johnson B. M.

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmaceutical Science,Pharmacology

Reference32 articles.

1. Hepatitis C Virus NS5A Replication Complex Inhibitors: The Discovery of Daclatasvir

2. Hepatitis C Virus NS5A Replication Complex Inhibitors. Part 6: Discovery of a Novel and Highly Potent Biarylimidazole Chemotype with Inhibitory Activity Toward Genotypes 1a and 1b Replicons

3. HCV NS5A replication complex inhibitors. Part 5: Discovery of potent and pan-genotypic glycinamide cap derivatives

4. Tiracizine disposition in healthy volunteers with reference to the debrisoquine oxidation phenotype [letter]

5. Efficient Initiation of HCV RNA Replication in Cell Culture

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