Differences in the Central Nervous System Distribution and Pharmacology of the Mouse 5-Hydroxytryptamine-6 Receptor Compared with Rat and Human Receptors Investigated by Radioligand Binding, Site-Directed Mutagenesis, and Molecular Modeling-Reference-Cited by-同舟云学术

Differences in the Central Nervous System Distribution and Pharmacology of the Mouse 5-Hydroxytryptamine-6 Receptor Compared with Rat and Human Receptors Investigated by Radioligand Binding, Site-Directed Mutagenesis, and Molecular Modeling

Published:2003-11-26 Issue:6 Volume:64 Page:1295-1308
ISSN:0026-895X
Container-title:Molecular Pharmacology
language:en
Short-container-title:Mol Pharmacol

Author:

Hirst Warren D.,Abrahamsen Bjarke,Blaney Frank E.,Calver Andrew R.,Aloj Lucia,Price Gary W.,Medhurst Andrew D.

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmacology,Molecular Medicine

Reference43 articles.

1. Investigation of stretching behaviour induced by the selective 5-HT6 receptor antagonist, Ro 04-6790, in rats

2. G-Protein Coupled Receptors: Models, Mutagenesis, and Drug Design

3. Stepwise Modulation of Neurokinin-3 and Neurokinin-2 Receptor Affinity and Selectivity in Quinoline Tachykinin Receptor Antagonists

4. Blaney FE and Tennant M (1996) Computational tools and results in the construction of G protein-coupled receptor models, in Membrane Protein Models (Findlay JBC ed) pp 161-176, Bios Scientific Publishers Ltd., Oxford.

Cited by 207 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Synthesis and Structure–Activity Relationships of 2,5-Dimethoxy-4-Substituted Phenethylamines and the Discovery of CYB210010: A Potent, Orally Bioavailable and Long-Acting Serotonin 5-HT₂ Receptor Agonist;Journal of Medicinal Chemistry;2024-04-09

2. SB-258585 reduces food motivation while blocking 5-HT6 receptors in the non-human primate striatum;Progress in Neuro-Psychopharmacology and Biological Psychiatry;2024-04

3. WAY-208466, a 5-HT6 receptor agonist, increases food motivation in primates: A behavioural and PET imaging study opening perspectives in eating disorders;Neuroscience Applied;2024

4. Selective 5-HT6 Receptor Ligands (Agonist and Antagonist) Show Different Effects on Antipsychotic Drug-Induced Metabolic Dysfunctions in Rats;Pharmaceuticals;2023-01-20

5. Spatiotemporal dynamics of 5-HT6 receptor ciliary localization during mouse brain development;Neurobiology of Disease;2023-01