Improved Brain Uptake and Pharmacological Activity Profile of Morphine-6-Glucuronide Using a Peptide Vector-Mediated Strategy-Reference-Cited by-同舟云学术

Improved Brain Uptake and Pharmacological Activity Profile of Morphine-6-Glucuronide Using a Peptide Vector-Mediated Strategy

Published:2005-01-12 Issue:2 Volume:313 Page:712-719
ISSN:0022-3565
Container-title:Journal of Pharmacology and Experimental Therapeutics
language:en
Short-container-title:J Pharmacol Exp Ther

Author:

Temsamani Jamal,Bonnafous Cécile,Rousselle Christophe,Fraisse Yannik,Clair Philippe,Granier Luc-André,Rees Anthony R.,Kaczorek Michel,Scherrmann Jean-Michel

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmacology,Molecular Medicine

Reference40 articles.

1. Morphine-6-glucuronide: Analgesic effects and receptor binding profile in rats

2. Peptide-vector strategy bypasses P-glycoprotein efflux, and enhances brain transport and solubility of paclitaxel

3. Evidence for an active transport of morphine-6-β-d-glucuronide but not P-glycoprotein-mediated at the blood-brain barrier

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