Antibody Drug Conjugates Differentiate Uptake and DNA Alkylation of Pyrrolobenzodiazepines in Tumors from Organs of Xenograft Mice-Reference-Cited by-同舟云学术

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Antibody Drug Conjugates Differentiate Uptake and DNA Alkylation of Pyrrolobenzodiazepines in Tumors from Organs of Xenograft Mice

Published:2016-09-28 Issue:12 Volume:44 Page:1958-1962
ISSN:0090-9556
Container-title:Drug Metabolism and Disposition
language:en
Short-container-title:Drug Metab Dispos

Author:

Ma Yong,Khojasteh S. Cyrus,Hop Cornelis E.C.A.,Erickson Hans K.,Polson Andrew,Pillow Thomas H.,Yu Shang-Fan,Wang Hong,Dragovich Peter S.,Zhang Donglu

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmaceutical Science,Pharmacology

Reference20 articles.

1. Comparison of Six Methods of Extracting Mycobacterium tuberculosis DNA from Processed Sputum for Testing by Quantitative Real-Time PCR

2. The XPF-ERCC1 endonuclease and homologous recombination contribute to the repair of minor groove DNA interstrand crosslinks in mammalian cells produced by the pyrrolo[2,1-c][1,4]benzodiazepine dimer SJG-136

3. Alkylation damage in DNA and RNA—repair mechanisms and medical significance

4. Balancing repair and tolerance of DNA damage caused by alkylating agents

5. Design, Synthesis, and Evaluation of a Novel Pyrrolobenzodiazepine DNA-Interactive Agent with Highly Efficient Cross-Linking Ability and Potent Cytotoxicity

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1. On Demand Bioorthogonal Switching of an Antibody-Conjugated SPECT Probe to a Cytotoxic Payload: from Imaging to Therapy;Journal of the American Chemical Society;2024-07-01

2. Optimizing Solid Tumor Treatment with Antibody–drug Conjugates Using Agent-Based Modeling: Considering the Role of a Carrier Dose and Payload Class;Pharmaceutical Research;2024-05-28

3. The Importance of Tracking “Missing” Metabolites: How and Why?;Journal of Medicinal Chemistry;2023-09-28

4. Anticancer alkylating agents;New Strategies Targeting Cancer Metabolism;2022

5. Cellular-Resolution Imaging of Bystander Payload Tissue Penetration from Antibody-Drug Conjugates;Molecular Cancer Therapeutics;2021-12-15

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