Species Differences in the Oxidative Desulfurization of a Thiouracil-Based Irreversible Myeloperoxidase Inactivator by Flavin-Containing Monooxygenase Enzymes-Reference-Cited by-同舟云学术

Species Differences in the Oxidative Desulfurization of a Thiouracil-Based Irreversible Myeloperoxidase Inactivator by Flavin-Containing Monooxygenase Enzymes

Published:2016-04-14 Issue:8 Volume:44 Page:1262-1269
ISSN:1521-009X
Container-title:Drug Metabolism and Disposition
language:en
Short-container-title:Drug Metabolism and Disposition

Author:

Eng H.,Sharma R.,Wolford A.,Di L.,Ruggeri R. B.,Buckbinder L.,Conn E. L.,Dalvie D. K.,Kalgutkar A. S.

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmaceutical Science,Pharmacology

Reference56 articles.

1. In Vitro and In Vivo Mechanistic Studies toward Understanding the Role of 1-Aminobenzotriazole in Rat Drug-Drug Interactions

2. Monooxygen donation potential of 4a-hydroperoxyflavins as compared with those of a percarboxylic acid and other hydroperoxides. Monooxygen donation to olefin, tertiary amine, alkyl sulfide, and iodide ion

3. The use of the suicide CYP450 inhibitor ABT for distinguishing absorption and metabolism processes in in-vivo pharmacokinetic screens

4. Structural and Catalytic Properties of the Mammalian Flavin-Containing Monooxygenase

5. Role of hepatic flavin-containing monooxygenase 3 in drug and chemical metabolism in adult humans

Cited by 8 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Biotransformation research advances – 2023 year in review;Drug Metabolism Reviews;2024-07-11

2. In vitro and in vivo studies on the metabolism and pharmacokinetics of the selective gut microbial β-glucuronidase targeting compound Inh 1;Xenobiotica;2024-06-12

3. Biotransformation of the Novel Myeloperoxidase Inhibitor AZD4831 in Preclinical Species and Humans;Drug Metabolism and Disposition;2023-01-18

4. Non-cytochrome P450 enzymes involved in the oxidative metabolism of xenobiotics: Focus on the regulation of gene expression and enzyme activity;Pharmacology & Therapeutics;2021-10

5. Drug Metabolism: Other Phase I Enzymes;Reference Module in Biomedical Sciences;2021