Design, Preparation, and Characterization of High-Activity Mutants of Human Butyrylcholinesterase Specific for Detoxification of Cocaine-Reference-Cited by-同舟云学术

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Design, Preparation, and Characterization of High-Activity Mutants of Human Butyrylcholinesterase Specific for Detoxification of Cocaine

Published:2010-10-22 Issue:2 Volume:79 Page:290-297
ISSN:0026-895X
Container-title:Molecular Pharmacology
language:en
Short-container-title:Mol Pharmacol

Author:

Xue Liu,Ko Mei-Chuan,Tong Min,Yang Wenchao,Hou Shurong,Fang Lei,Liu Junjun,Zheng Fang,Woods James H.,Tai Hsin-Hsiung,Zhan Chang-Guo

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmacology,Molecular Medicine

Reference42 articles.

1. Butyrylcholinesterase alters the aggregation of β amyloid;Barber;Soc Neurosci Abstr,1996

2. Braman J Papworth C Greener A (2000) Site-Directed Mutagenesis Using Double-Stranded Plasmid DNA Templates, in The Nucleic Acid Protocols Handbook ( Rapley R ed) pp 835–844, Humana Press, Totowa, NJ.

3. A Thermally Stable Form of Bacterial Cocaine Esterase: A Potential Therapeutic Agent for Treatment of Cocaine Abuse

4. A Cocaine Hydrolase Engineered from Human Butyrylcholinesterase Selectively Blocks Cocaine Toxicity and Reinstatement of Drug Seeking in Rats

5. Treating cocaine addiction with viruses

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1. In vitro and in vivo stability of a highly efficient long-acting cocaine hydrolase;Scientific Reports;2024-05-13

2. Long-lasting blocking of interoceptive effects of cocaine by a highly efficient cocaine hydrolase in rats;Scientific Reports;2024-01-09

3. Human Butyrylcholinesterase Mutants for (−)-Cocaine Hydrolysis: A Correlation Relationship between Catalytic Efficiency and Total Hydrogen Bonding Energy with an Oxyanion Hole;The Journal of Physical Chemistry B;2023-12-08

4. Catalytic activities of a highly efficient cocaine hydrolase for hydrolysis of biologically active cocaine metabolites norcocaine and benzoylecgonine;Scientific Reports;2023-01-12

5. Kinetic characterization of an efficient cocaine hydrolase against toxic metabolites of cocaine;Organic & Biomolecular Chemistry;2023

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