Mutations Distal to the Substrate Site Can Affect Varicella Zoster Virus Thymidine Kinase Activity: Implications for Drug Design-Reference-Cited by-同舟云学术

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Mutations Distal to the Substrate Site Can Affect Varicella Zoster Virus Thymidine Kinase Activity: Implications for Drug Design

Published:2006-03-23 Issue:6 Volume:69 Page:1891-1896
ISSN:0026-895X
Container-title:Molecular Pharmacology
language:en
Short-container-title:Mol Pharmacol

Author:

El Omari Kamel,Liekens Sandra,Bird Louise E.,Balzarini Jan,Stammers David K.

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmacology,Molecular Medicine

Reference22 articles.

1. Highly Purified Recombinant Varicella Zoster Virus Thymidine Kinase Is a Homodimer

2. Antiviral activity of ganciclovir elaidic acid ester against herpesviruses

3. Structure-activity relationship of the affinity of 5-substituted uracil nucleoside analogues for varicella-zoster virus thymidine kinase and their activity against varicella-zoster virus

4. Bicyclic pyrimidine nucleoside analogues (BCNAs) as highly selective and potent inhibitors of varicella-zoster virus replication

5. Chemotherapy of varicella-zoster virus by a novel class of highly specific anti-VZV bicyclic pyrimidine nucleosides

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1. Harnessing Conformational Plasticity to Generate Designer Enzymes;Journal of the American Chemical Society;2020-06-04

2. Manipulating Conformational Dynamics To Repurpose Ancient Proteins for Modern Catalytic Functions;ACS Catalysis;2020-03-31

3. β-L-1-[5-(E-2-Bromovinyl)-2-(hydroxymethyl)-1,3-dioxolan-4-yl)] uracil (L-BHDU) effectiveness against varicella-zoster virus and herpes simplex virus type 1 depends on thymidine kinase activity;2020-02-14

4. Structural Determinants for Substrate Selectivity in Guanine Deaminase Enzymes of the Amidohydrolase Superfamily;Biochemistry;2019-07-08

5. Thymidine kinase and protein kinase in drug-resistant herpesviruses: Heads of a Lernaean Hydra;Drug Resistance Updates;2018-03

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