Methemoglobin Formation by Triapine, Di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone (Dp44mT), and Other Anticancer Thiosemicarbazones: Identification of Novel Thiosemicarbazones and Therapeutics That Prevent This Effect

Author:

Quach Patricia,Gutierrez Elaine,Basha Maram Talal,Kalinowski Danuta S.,Sharpe Philip C.,Lovejoy David B.,Bernhardt Paul V.,Jansson Patric J.,Richardson Des R.

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmacology,Molecular Medicine

Reference48 articles.

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2. Iron Chelators of the Dipyridylketone Thiosemicarbazone Class: Precomplexation and Transmetalation Effects on Anticancer Activity

3. Examination of the antiproliferative activity of iron chelators: multiple cellular targets and the different mechanism of action of triapine compared with desferrioxamine and the potent pyridoxal isonicotinoyl hydrazone analogue 311;Chaston;Clin Cancer Res,2003

4. Accuracy of methemoglobin measurements

5. The aerobic reduction of Fe(III) complexes by hemoglobin and myoglobin;Eguchi;J Biol Chem,1984

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