Metabolic Activation of the Indoloquinazoline Alkaloids Evodiamine and Rutaecarpine by Human Liver Microsomes: Dehydrogenation and Inactivation of Cytochrome P450 3A4-Reference-Cited by-同舟云学术

Metabolic Activation of the Indoloquinazoline Alkaloids Evodiamine and Rutaecarpine by Human Liver Microsomes: Dehydrogenation and Inactivation of Cytochrome P450 3A4

Published:2014-04-02 Issue:6 Volume:42 Page:1044-1054
ISSN:0090-9556
Container-title:Drug Metabolism and Disposition
language:en
Short-container-title:Drug Metab Dispos

Author:

Wen Bo,Roongta Vikram,Liu Liling,Moore David J.

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmaceutical Science,Pharmacology

Reference36 articles.

1. Cytotoxicity and P-Glycoprotein Modulating Effects of Quinolones and Indoloquinazolines from the Chinese Herb Evodia rutaecarpa

2. Mass spectrometry in the analysis of glutathione conjugates

3. Negative Ion Tandem Mass Spectrometry for the Detection of Glutathione Conjugates

4. New Tricks for an Old Natural Product: Discovery of Highly Potent Evodiamine Derivatives as Novel Antitumor Agents by Systemic Structure–Activity Relationship Analysis and Biological Evaluations

5. Evodiamine, a constituent of Evodiae Fructus, induces anti-proliferating effects in tumor cells

Cited by 42 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Rutaecarpine Aggravates Acetaminophen-Induced Acute Liver Injury by Inducing CYP1A2;Toxics;2024-07-18

2. Metabolic characteristics of evodiamine were associated with its hepatotoxicity via PPAR/PI3K/AKT/NF-кB/tight junction pathway-mediated apoptosis in zebrafish;Ecotoxicology and Environmental Safety;2024-07

3. TFA Mediated Ring-Opening for Evodiamine to Prepare Novel Tryptamine Derivatives;Journal of the chemical society of pakistan;2024

4. The inhibitory effect of licorice on the hepatotoxicity induced by the metabolic activation of Euodiae Fructus;Journal of Ethnopharmacology;2024-01

5. Major Indole Alkaloids in Evodia Rutaecarpa: The Latest Insights and Review of Their Impact on Gastrointestinal Diseases;Biomedicine & Pharmacotherapy;2023-11