Disposition of the Dipeptidyl Peptidase 4 Inhibitor Sitagliptin in Rats and Dogs-Reference-Cited by-同舟云学术

Disposition of the Dipeptidyl Peptidase 4 Inhibitor Sitagliptin in Rats and Dogs

Published:2007-01-12 Issue:4 Volume:35 Page:525-532
ISSN:0090-9556
Container-title:Drug Metabolism and Disposition
language:en
Short-container-title:Drug Metab Dispos

Author:

Beconi Maria G.,Reed James R.,Teffera Yohannes,Xia Yuan-Qing,Kochansky Christopher J.,Liu David Q.,Xu Shiyao,Elmore Charles S.,Ciccotto Suzanne,Hora Donald F.,Stearns Ralph A.,Vincent Stella H.

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmaceutical Science,Pharmacology

Reference34 articles.

1. Inhibition of Dipeptidyl Peptidase-4 Reduces Glycemia, Sustains Insulin Levels, and Reduces Glucagon Levels in Type 2 Diabetes

2. Mass spectrometry in the analysis of glutathione conjugates

3. Inhibition of dipeptidyl peptidase IV with NVP-DPP728 increases plasma GLP-1 (7-36 amide) concentrations and improves oral glucose tolerance in obese Zucker rats

4. METABOLISM AND PHARMACOKINETICS OF A DIPEPTIDYL PEPTIDASE IV INHIBITOR IN RATS, DOGS, AND MONKEYS WITH SELECTIVE CARBAMOYL GLUCURONIDATION OF THE PRIMARY AMINE IN DOGS

5. Pharmacokinetic and pharmacodynamic properties of multiple oral doses of sitagliptin, a dipeptidyl peptidase-IV inhibitor: A double-blind, randomized, placebo-controlled study in healthy male volunteers

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