Discovery and Preclinical Characterization of GSK1278863 (Daprodustat), a Small Molecule Hypoxia Inducible Factor–Prolyl Hydroxylase Inhibitor for Anemia-Reference-Cited by-同舟云学术

Discovery and Preclinical Characterization of GSK1278863 (Daprodustat), a Small Molecule Hypoxia Inducible Factor–Prolyl Hydroxylase Inhibitor for Anemia

Published:2017-09-19 Issue:3 Volume:363 Page:336-347
ISSN:0022-3565
Container-title:Journal of Pharmacology and Experimental Therapeutics
language:en
Short-container-title:J Pharmacol Exp Ther

Author:

Ariazi Jennifer L.,Duffy Kevin J.,Adams David F.,Fitch Duke M.,Luo Lusong,Pappalardi Melissa,Biju Mangatt,DiFilippo Erin Hugger,Shaw Tony,Wiggall Ken,Erickson-Miller Connie

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmacology,Molecular Medicine

Reference75 articles.

1. Structural Basis for Inhibition of the Fat Mass and Obesity Associated Protein (FTO)

2. Effects of daprodustat, a novel hypoxia-inducible factor prolyl hydroxylase inhibitor on anemia management in Japanese hemodialysis subjects;Akizawa;Am J Nephrol,2017

3. Induction of Heart Valve Lesions by Small-Molecule ALK5 Inhibitors

5. High Hematocrit Resulting from Administration of Erythropoiesis-stimulating Agents Is Not Fully Predictive of Mortality or Toxicities in Preclinical Species

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