Structural Basis for Inhibition of the Fat Mass and Obesity Associated Protein (FTO)-Reference-Cited by-同舟云学术

Structural Basis for Inhibition of the Fat Mass and Obesity Associated Protein (FTO)

Published:2013-04-23 Issue:9 Volume:56 Page:3680-3688
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Aik WeiShen¹,Demetriades Marina¹,Hamdan Muhammad K. K.¹,Bagg Eleanor. A. L.¹,Yeoh Kar Kheng¹,Lejeune Clarisse¹,Zhang Zhihong¹,McDonough Michael A.¹,Schofield Christopher J.¹

Affiliation:

1. Chemistry Research Laboratory, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, United Kingdom

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm400193d

Reference32 articles.

1. A Common Variant in the FTO Gene Is Associated with Body Mass Index and Predisposes to Childhood and Adult Obesity

2. A Mouse Model for the Metabolic Effects of the Human Fat Mass and Obesity Associated FTO Gene

3. Overexpression of Fto leads to increased food intake and results in obesity

4. The Obesity-Associated FTO Gene Encodes a 2-Oxoglutarate-Dependent Nucleic Acid Demethylase

5. Oxidative demethylation of 3-methylthymine and 3-methyluracil in single-stranded DNA and RNA by mouse and human FTO

Cited by 132 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Small molecules that regulate the N6-methyladenosine RNA modification as potential anti-cancer agents;European Journal of Medicinal Chemistry;2024-08

2. MM/GB(PB)SA integrated with molecular docking and ADMET approach to inhibit the fat-mass-and-obesity-associated protein using bioactive compounds derived from food plants used in traditional Chinese medicine;Pharmacological Research - Modern Chinese Medicine;2024-06

3. Small molecule inhibitors targeting m6A regulators;Journal of Hematology & Oncology;2024-05-06

4. Targeting RNA modifications with pharmacological agents: New frontiers in cancer therapy;Cancer Medicine;2024-03-28

5. Inhibition of OGFOD1 by FG4592 confers neuroprotection by activating unfolded protein response and autophagy after ischemic stroke;Journal of Translational Medicine;2024-03-07