Brain Penetration of the Oral Immunomodulatory Drug FTY720 and Its Phosphorylation in the Central Nervous System during Experimental Autoimmune Encephalomyelitis: Consequences for Mode of Action in Multiple Sclerosis-Reference-Cited by-同舟云学术

Brain Penetration of the Oral Immunomodulatory Drug FTY720 and Its Phosphorylation in the Central Nervous System during Experimental Autoimmune Encephalomyelitis: Consequences for Mode of Action in Multiple Sclerosis

Published:2007-08-06 Issue:2 Volume:323 Page:469-475
ISSN:0022-3565
Container-title:Journal of Pharmacology and Experimental Therapeutics
language:en
Short-container-title:J Pharmacol Exp Ther

Author:

Foster Carolyn A.,Howard Laurence M.,Schweitzer Alain,Persohn Elke,Hiestand Peter C.,Balatoni Balázs,Reuschel Roland,Beerli Christian,Schwartz Manuela,Billich Andreas

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmacology,Molecular Medicine

Reference40 articles.

1. Astrocyte–endothelial interactions at the blood–brain barrier

2. Mice Deficient in Sphingosine Kinase 1 Are Rendered Lymphopenic by FTY720

3. FTY720 sustains and restores neuronal function in the DA rat model of MOG-induced experimental autoimmune encephalomyelitis

4. FTY720, an immunomodulatory sphingolipid mimetic: translation of a novel mechanism into clinical benefit in multiple sclerosis

5. Phosphorylation of the Immunomodulatory Drug FTY720 by Sphingosine Kinases

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