Age-Dependent Kinetics and Metabolism of Dichloroacetate: Possible Relevance to Toxicity-Reference-Cited by-同舟云学术

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Age-Dependent Kinetics and Metabolism of Dichloroacetate: Possible Relevance to Toxicity

Published:2007-12-20 Issue:3 Volume:324 Page:1163-1171
ISSN:0022-3565
Container-title:Journal of Pharmacology and Experimental Therapeutics
language:en
Short-container-title:J Pharmacol Exp Ther

Author:

Shroads Albert L.,Guo Xu,Dixit Vaishali,Liu Hui-Ping,James Margaret O.,Stacpoole Peter W.

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmacology,Molecular Medicine

Reference24 articles.

1. Ammini CV and Stacpoole PW (2003) Biotransformation, toxicology and pharmacogenomics of dichloroacetate, in The Handbook of Environmental Chemistry (Gribble GW ed) pp 215–234, Springer-Verlag New York Inc., New York.

2. Pharmacologic or genetic ablation of maleylacetoacetate isomerase increases levels of toxic tyrosine catabolites in rodents

3. Effects of age and dietary restriction on liver glutathione transferase activities in Lobund-Wistar rats

4. Inhibition of Glutathione S-Transferase ζ and Tyrosine Metabolism by Dichloroacetate: A Potential Unifying Mechanism for Its Altered Biotransformation and Toxicity

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