Pharmacologic or genetic ablation of maleylacetoacetate isomerase increases levels of toxic tyrosine catabolites in rodents

Author:

Ammini Chandramohan V,Fernandez-Canon Jose,Shroads Albert L,Cornett Rachel,Cheung Jang,James Margaret O,Henderson George N,Grompe Markus,Stacpoole Peter W

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference39 articles.

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2. Ammini CV, Stacpoole PW. Biotransformation, toxicology and pharmacogenomics of dichloroacetate. In: Gribble GW, editor. Natural production of organohalogen compounds, vol. 3/P in the series ‘The handbook of environmental chemistry’. Springer-Verlag; 2003. p. 215–34.

3. Pharmacokinetics, metabolism and toxicology of dichloroacetate;Stacpoole;Drug Metab. Rev.,1998

4. Lactic acidosis and other mitochondrial disorders;Stacpoole;Metabolism,1997

5. The pharmacology of dichloroacetate;Stacpoole;Metabolism,1989

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