Discovery and Characterization of a G Protein–Biased Agonist That Inhibits β-Arrestin Recruitment to the D2 Dopamine Receptor-Reference-Cited by-同舟云学术

Discovery and Characterization of a G Protein–Biased Agonist That Inhibits β-Arrestin Recruitment to the D2 Dopamine Receptor

Published:2014-04-22 Issue:1 Volume:86 Page:96-105
ISSN:0026-895X
Container-title:Molecular Pharmacology
language:en
Short-container-title:Mol Pharmacol

Author:

Free R. Benjamin,Chun Lani S.,Moritz Amy E.,Miller Brittney N.,Doyle Trevor B.,Conroy Jennie L.,Padron Adrian,Meade Julie A.,Xiao Jingbo,Hu Xin,Dulcey Andrés E.,Han Yang,Duan Lihua,Titus Steve,Bryant-Genevier Melanie,Barnaeva Elena,Ferrer Marc,Javitch Jonathan A.,Beuming Thijs,Shi Lei,Southall Noel T.,Marugan Juan J.,Sibley David R.

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmacology,Molecular Medicine

Reference44 articles.

1. Molecular Determinants of Allosteric Modulation at the M1 Muscarinic Acetylcholine Receptor

2. Discovery of -Arrestin-Biased Dopamine D2 Ligands for Probing Signal Transduction Pathways Essential for Antipsychotic Efficacy

3. N-(3-Fluoro-4-(4-(2-methoxy or 2,3-dichlorophenyl)piperazine-1-yl)butyl)arylcarboxamides as Selective Dopamine D3 Receptor Ligands: Critical Role of the Carboxamide Linker for D3 Receptor Selectivity

4. Cell type–specific regulation of DARPP-32 phosphorylation by psychostimulant and antipsychotic drugs

5. More than a Simple Lipophilic Contact: A Detailed Thermodynamic Analysis of Nonbasic Residues in the S1 Pocket of Thrombin

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