Reactive Metabolite Trapping Studies on Imidazo- and 2-Methylimidazo[2,1-b]thiazole-Based Inverse Agonists of the Ghrelin Receptor-Reference-Cited by-同舟云学术

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Reactive Metabolite Trapping Studies on Imidazo- and 2-Methylimidazo[2,1-b]thiazole-Based Inverse Agonists of the Ghrelin Receptor

Published:2013-04-22 Issue:7 Volume:41 Page:1375-1388
ISSN:0090-9556
Container-title:Drug Metabolism and Disposition
language:en
Short-container-title:Drug Metab Dispos

Author:

Kalgutkar Amit S.,Ryder Tim F.,Walker Gregory S.,Orr Suvi T. M.,Cabral Shawn,Goosen Theunis C.,Lapham Kimberly,Eng Heather

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmaceutical Science,Pharmacology

Reference45 articles.

1. Cyanide Trapping of Iminium Ion Reactive Intermediates Followed by Detection and Structure Identification Using Liquid Chromatography−Tandem Mass Spectrometry (LC-MS/MS)

2. Mass spectrometry in the analysis of glutathione conjugates

3. Role of Ghrelin in the Pathophysiology of Eating Disorders

4. The metabolism of acetamidothiazoles in the rat. 2-Acetamido-, 2-acetamido-4-methyl- and 2-acetamido-4-phenyl-thiazole

5. Metabolism of Meloxicam in human liver involves cytochromes P4502C9 and 3A4

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