Prediction of Human Pharmacokinetics in 2013 and Beyond
Author:
Publisher
American Society for Pharmacology & Experimental Therapeutics (ASPET)
Subject
Pharmaceutical Science,Pharmacology
Reference17 articles.
1. Blobaum AL, Bridges TM, Byers FW, Turlington M, Mattmann M, Morrison RD, Mackie J,Lavreysen H, Bartolome JM, MacDonald GJ, et al. (2013) Hetertropic activity of P450 3A by a positive allosteric modulator of metabotrophic glutamate receptor 5: In vitro to in vivo translation and potential impact on clinicality relevant drug-drug interactions. Drug Metab Dispos 41:2066–2075.
2. Drug Metabolites as Cytochrome P450 Inhibitors: A Retrospective Analysis and Proposed Algorithm for Evaluation of the Pharmacokinetic Interaction Potential of Metabolites in Drug Discovery and Development
3. Meeting the Challenge of Predicting Hepatic Clearance of Compounds Slowly Metabolized by Cytochrome P450 Using a Novel Hepatocyte Model, HepatoPac
4. A Perspective on the Prediction of Drug Pharmacokinetics and Disposition in Drug Research and Development
5. In Vitro–In Vivo Correlation for Low-Clearance Compounds Using Hepatocyte Relay Method
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